If we left Friday afternoon stayed in Nova for the night..Leave in the am around 7:30 am..we can drive to end of SC or beginning of Georgia spend the night there and drive around 3hrs to Daytona from Georgia arrive on Sunday afternoon..
From my personal experience driving there so many times so far this year with my move(6x so far this yr) i have Left Saturday from North Jersey on a Saturday 2am and arrived Orlando the same Saturday at around 9pm..no crazy speeds just 85mph most of the way down..